Human and Chemical Risk Assessment

Our Expertise

• Agrochemicals

  Our work for agrochemicals clients encompasses all aspects of the process, including advocacy, exposure modelling, environmental fate, spatial analysis and statistics, ecotoxicology, aquatic testing, toxicology, risk assessment, dossier section preparation, software development, training, and product stewardship.

• Biocides

  We have a wide range of experience with various biocide product types and can offer expert guidance on the requirements of the Biocidal Products Regulation. We can provide a full dossier preparation and support service throughout the entire regulatory process.

• Veterinary medicines

  In addition to our regular offering, our veterinary medicine specialists can provide non-clinical regulatory support for your product through the entire regulatory process, including product development and defence strategies, product advocacy meetings with member state regulators, data gap analysis, literature reviews, placement and monitoring of studies, and environmental risk assessment.

• Industrial and speciality chemicals

  We provide chemical regulatory support to a range of industries, including chemical manufacturers and importers, aerospace, automotive, food additives, fragrances, fire retardants, ceramics, colourants, resins, cleaning products, and many more. We specialise in new substances, substances that are difficult to identify, and substances where properties or uses require a non-standard approach to toxicology or eco-toxicology testing, exposure scenarios and evaluations.

• Environmental fate and exposure

  Our team calculates and predicts environmental concentrations. Furthermore, we design, characterise and implement higher-tier exposure scenarios for risk refinement, including developing software to facilitate bespoke risk assessment approaches. We undertake spatially distributed, probabilistic and catchment-scale exposure modelling and risk assessments. Our dossier services include data gap analysis with subsequent study monitoring; preparation of environmental fate (efate) dossier sections for formulated products and active substances; discussions, liaison and strategy development with authorities; and post-submission support. Our in-house field-fate team can design, deliver and interpret higher-tier efate studies to good laboratory-practice-standards that address specific regulatory concerns.

• Ecotoxicology and wildlife risk assessment

  We work together with our efate, exposure modelling, aquatic testing and toxicology colleagues to develop interdisciplinary approaches to ensure optimal solutions. We can undertake assessments of endocrine disruptor properties and have full use of in-house aquatic ecotoxicology testing facilities. We also offer data analysis for new and existing ecotoxicological datasets to derive effect concentrations and minimum detectable differences.

• Toxicology and human health risk assessment

  We provide expert advice and support for general chemicals, plant protection products, biocides, foods and food contact materials, and cosmetics, including reviews of existing toxicological data sets and undertaking data gap analyses. We are experts in using various alternative approaches and tools where needed to minimise animal use and keep testing costs to a minimum. Our dossier services include preparation of chemical safety reports, study summaries, discussions, liaison and strategy development with authorities, and post-submission support.

• Software

  In partnership with our software development team in ADAS, we have extensive experience of developing bespoke desktop and web-based software covering a diverse array of user needs for a range of government and commercial clients in various chemical sectors.

• Training

  We offer general and bespoke training courses on various aspect of the environmental risk assessment process from standard approaches to higher tier refinements for all chemical sectors.